Progressive multifocal leukoencephalopathy
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Progressive multifocal leukoencephalopathy (PML) is an extremely rare disorder that damages myelin, the material protecting the nerves of the white matter in the brain. PML is caused by the JC virus, which is triggered by poor immune function. Occurring in 4% of AIDS patients, PML can cause headaches, memory loss, aphasia, vision problems, loss of coordination and progressive weakness of arms and legs.
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