When I have muscle spasms I used to have 3 tabs of 900mg of Gabapentin and now I shifted to Methadone on doctors advice having 2 or 3 tabs of 10mg of Methadone, I take this with 900mg or Gabapentin 3 x a day, I also dose with Tizanidine 4mg when needed, and also the anti-inflammatory, I am under control; with all these dosage I never had an idea that Methadone would work as well if I did not take the other meds. I use Wellbutrin, at the time of Depression. This would also affect my back. Concluding the severe dosage of many meds I think this cures the best with the least side effects. I tried a lot finally methadone works for me.