What Is Osteogenesis Imperfecta?

0 votes
asked Apr 4, 2010 by anonymous

1 Answer

0 votes
Osteogenesis Imperfecta is also known as the Brittle Bone Disease. This is a congenital condition and can also be inherited and described as an abnormal fragility of the bone.

The causes of this condition can be brought about by different factors. The bone defects can be because it is inherited in an autosomal pattern from the patient's affected parent. It can also be because of the spontaneous mutation of an egg or sperm in the development of a child. Some cases can also be because of an inheritance known as mosaicism, this happens when none of the parents are affected but one of them carries an affected egg or sperm cell.

Here are the Symptoms of Osteogenesis Imperfecta:

- having a broken or fractured bones, this can be present ate birth or a person who have two or more broken bones in a single time.
- deformities in the arms
- deformities in the legs
- kyphosis
- kyphoscoliosis
- deafness
- short stature
- having a low nasal bridge
- having abnormalities in teeth
- easily being bruised
- hypermobility
- joint laxity
- flat feet
- bowed legs
- pectus excavatum and carinatum
answered Apr 4, 2010 by anonymous