Potential Side Effects and Interactions of Zometic With Other Medicines

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The patient is a woman of 95 years old with Parkinson since 30 years. Parkinson treatment is with Prolopa and in addition she takes Ipran, Alprazolam, Coumedin and occasionaly Ibuprofeno. Lately, she has been experiencing allucinations and mental confusion, mood changes and bad temper. These symptoms have become more frequent but she  returns to normal. Can these symptoms be associated with the use of Zometic for already between six months and a year? Thanks.
asked Sep 9, 2010 by anonymous

1 Answer

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Zometic (zopiclone) is a non-benzodiazepine hypnotic agent used in the treatment of insomnia. Zometic is indicated for the short term treatment (1-4 weeks max) of insomnia where sleep initiation or sleep maintenance are prominent symptoms. Long-term use is not recommended as tolerance, dependence and addiction can occur with prolonged use.
The hallucinations, mental confusion, mood changes, and bad temper, these are all side effects of zopiclone. You have stated that she has been on prolonged used of zopiclone. Prolonged use can actually make the body become accustomed to the effects of zopiclone. Was the dose reduced or stopped? If yes, then this indicates withdrawal symptoms. Let us check below for possible drug interactions of her medications.
Prolopa (levodopa+benserazide) and zopiclone – no  known drug interaction
Ipran (escitalopram) and zopiclone – may interact. Drink these separately.
Alprazolam and zopiclone - may interact. Drink these separately.
Coumadin and zopiclone - no  known drug interaction
Ibuprofen and zopiclone - no  known drug interaction
answered May 1, 2013 by donnap Diamond Guide (2,197 points)

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